Originally Posted by
drt1010
I am not sure. I see the conflict. What I read:
Twenty cases were treated in this study and showed a significant reduction of the viral
carriage at D6-post inclusion compared to controls, and much lower average carrying duration
than reported of untreated patients in the literature. Azithromycin added to
hydroxychloroquine was significantly more efficient for virus elimination.
The primary endpoint was virological clearance at day-6 post-inclusion. Secondary outcomes
were virological clearance overtime during the study period, clinical follow-up (body
temperature, respiratory rate, long of stay at hospital and mortality), and occurrence of side-effects.
When comparing the effect of hydroxychloroquine treatment as a single drug and the effect of
hydroxychloroquine and azithromyc in combination, the proportion of patients that had
negative PCR results in nasopharyngeal samples was significantly different between the two
groups at days 3-4-5 and 6 post-inclusion (Table 3). At day6 post-inclusion, 100% of patients
treated with hydroxychloroquine and azithromycin combination were virologicaly cured
comparing with 57.1% in patients treated with hydroxychloroquine only, and 12.5% in the
control group (p<0.001). These results are summarized in Figures 1 and 2. Drug effect was
significantly higher in patients with symptoms of URTI and LRTI, as compared to
asymptomatic patients with p<0.05.